• iron ion binding • demethylase activity • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen • metal ion binding • caffeine oxidase activity • heme binding • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • enzyme binding • oxidoreductase activity • aromatase activity • electron carrier activity • monooxygenase activity
• response to immobilization stress • 毒素代謝プロセス • steroid metabolic process • response to estradiol • alkaloid metabolic process • response to organic cyclic compound • 肺発生 • 脂質代謝 • exogenous drug catabolic process • epoxygenase P450 pathway • cellular response to cadmium ion • post-embryonic development • monocarboxylic acid metabolic process • response to organic substance • oxidative deethylation • oxidative demethylation • drug catabolic process • response to lipopolysaccharide • メチル化 • steroid catabolic process • omega-hydroxylase P450 pathway • dibenzo-p-dioxin metabolic process • heterocycle metabolic process • 細胞呼吸 • cellular aromatic compound metabolic process • 遺伝子発現調節 • hydrogen peroxide biosynthetic process • monoterpenoid metabolic process • drug metabolic process • xenobiotic metabolic process • oxidation-reduction process • response to drug • porphyrin-containing compound metabolic process • toxin biosynthetic process • cellular response to copper ion • 電子伝達系 • long-chain fatty acid biosynthetic process
^Fontana R, Lown K, Paine M, Fortlage L, Santella R, Felton J, Knize M, Greenberg A, Watkins P (1999). “Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P-glycoprotein levels in healthy volunteers”. Gastroenterology117 (1): 89–98. doi:10.1016/S0016-5085(99)70554-8. PMID 10381914.
^ ab Mentioned both in the reference named FASS and were previously mentioned in Wikipedia. Further contributions may follow other systems
^Swedish environmental classification of pharmaceuticals Facts for prescribers (Fakta för förskrivare)
^Edwards DJ, Bernier SM (1996). “Inhibitory effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man”. Life Sciences59 (13): 1025–1030. doi:10.1016/0024-3205(96)00417-1. PMID 8485024.
Meijerman I, Beijnen J, Schellens J (2006). “Herb-drug interactions in oncology: focus on mechanisms of induction”. Oncologist11 (7): 742–52. doi:10.1634/theoncologist.11-7-742. PMID 16880233.
参考文献
Smith G, Stubbins MJ, Harries LW, Wolf CR (1999). “Molecular genetics of the human cytochrome P450 monooxygenase superfamily.”. Xenobiotica28 (12): 1129–65. doi:10.1080/004982598238868. PMID 9890157.
Landi MT, Sinha R, Lang NP, Kadlubar FF (1999). “Human cytochrome P4501A2.”. IARC Sci. Publ. (148): 173–95. PMID 10493258.
Nelson DR, Zeldin DC, Hoffman SM, et al. (2004). “Comparison of cytochrome P450 (CYP)genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.”. Pharmacogenetics14 (1): 1–18. doi:10.1097/00008571-200401000-00001. PMID 15128046.
Ikeya K, Jaiswal AK, Owens RA, et al. (1990). “Human CYP1A2: sequence, gene structure, comparison with the mouse and rat orthologous gene, and differences in liver 1A2 mRNA expression.”. Mol. Endocrinol.3 (9): 1399–408. PMID 2575218.
Butler MA, Iwasaki M, Guengerich FP, Kadlubar FF (1989). “Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.”. Proc. Natl. Acad. Sci. U.S.A.86 (20): 7696–700. doi:10.1073/pnas.86.20.7696. PMID 2813353.
Quattrochi LC, Okino ST, Pendurthi UR, Tukey RH (1986). “Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6.”. DNA4 (5): 395–400. PMID 3000715.
Quattrochi LC, Pendurthi UR, Okino ST, et al. (1986). “Human cytochrome P-450 4 mRNA and gene: part of a multigene family that contains Alu sequences in its mRNA.”. Proc. Natl. Acad. Sci. U.S.A.83 (18): 6731–5. doi:10.1073/pnas.83.18.6731. PMID 3462722.
Wrighton SA, Campanile C, Thomas PE, et al. (1986). “Identification of a human liver cytochrome P-450 homologous to the major isosafrole-inducible cytochrome P-450 in the rat.”. Mol. Pharmacol.29 (4): 405–10. PMID 3517618.
Jaiswal AK, Nebert DW, McBride OW, Gonzalez FJ (1988). “Human P(3)450: cDNA and complete protein sequence, repetitive Alu sequences in the 3' nontranslated region, and localization of gene to chromosome 15.”. J. Exp. Pathol.3 (1): 1–17. PMID 3681487.
Eugster HP, Probst M, Würgler FE, Sengstag C (1993). “Caffeine, estradiol, and progesterone interact with human CYP1A1 and CYP1A2. Evidence from cDNA-directed expression in Saccharomyces cerevisiae.”. Drug Metab. Dispos.21 (1): 43–9. PMID 8095225.
Schweikl H, Taylor JA, Kitareewan S, et al. (1994). “Expression of CYP1A1 and CYP1A2 genes in human liver.”. Pharmacogenetics3 (5): 239–49. doi:10.1097/00008571-199310000-00003. PMID 8287062.
Yamazaki H, Inoue K, Mimura M, et al. (1996). “7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes.”. Biochem. Pharmacol.51 (3): 313–9. doi:10.1016/0006-2952(95)02178-7. PMID 8573198.
Hakkola J, Raunio H, Purkunen R, et al. (1996). “Detection of cytochrome P450 gene expression in human placenta in first trimester of pregnancy.”. Biochem. Pharmacol.52 (2): 379–83. doi:10.1016/0006-2952(96)00216-X. PMID 8694864.
Guengerich FP, Johnson WW (1998). “Kinetics of ferric cytochrome P450 reduction by NADPH-cytochrome P450 reductase: rapid reduction in the absence of substrate and variations among cytochrome P450 systems.”. Biochemistry36 (48): 14741–50. doi:10.1021/bi9719399. PMID 9398194.
Wacke R, Kirchner A, Prall F, et al. (1998). “Up-regulation of cytochrome P450 1A2, 2C9, and 2E1 in chronic pancreatitis.”. Pancreas16 (4): 521–8. doi:10.1097/00006676-199805000-00011. PMID 9598815.
Macé K, Bowman ED, Vautravers P, et al. (1998). “Characterisation of xenobiotic-metabolising enzyme expression in human bronchial mucosa and peripheral lung tissues.”. Eur. J. Cancer34 (6): 914–20. doi:10.1016/S0959-8049(98)00034-3. PMID 9797707.
Huang JD, Guo WC, Lai MD, et al. (1999). “Detection of a novel cytochrome P-450 1A2 polymorphism (F21L)in Chinese.”. Drug Metab. Dispos.27 (1): 98–101. PMID 9884316.
Tatemichi M, Nomura S, Ogura T, et al. (1999). “Mutagenic activation of environmental carcinogens by microsomes of gastric mucosa with intestinal metaplasia.”. Cancer Res.59 (16): 3893–8. PMID 10463577.
.everyoneloves__top-leaderboard:empty,.everyoneloves__mid-leaderboard:empty,.everyoneloves__bot-mid-leaderboard:empty{ height:90px;width:728px;box-sizing:border-box;
}
0
This is a simple project showing cubes on Unity, exported to android project and imported on Android studio. On maifest file it showed following warning: Expecting <uses-feature android:name="android.software.leanback" android:required="false" /> tag I have no information about it. And also on default emptyview android project does not use/mention this feature. I know it is required by TV's and such but why its not added by default? Why is this? And Should I concern about it?
android unity3d
0
I'm trying to update an entry in my database (postgresql). I'm having a problem with updating the query: INSERT INTO prices (price, product_id) SELECT product_price, commn_id FROM products_temp as prod WHERE NOT EXISTS (SELECT * FROM prices od WHERE prod.commn_id = od.product_id) OR prod.product_price != ( SELECT price FROM prices as p WHERE p.product_id = prod.commn_id order by p.end desc LIMIT 1 ) Query works fine when i delete: OR prod.product_price != ( SELECT price FROM prices as p WHERE p.product_id = prod.commn_id order by p.end desc LIMIT 1 ) So it seems to me that it's looping through this operation. My question is, how can I fix it?
sql postgresql
0
My application was working fine until I decided to go with lazy loading: So, my shared component looks like this: import { Component, Renderer2 } from '@angular/core'; export interface FormModel { captcha?: string; } @Component({ selector: 'app-layout', templateUrl: './app-layout.component.html', styleUrls: ['./app-layout.css'] }) export class FullLayoutComponent { } app-layout.component.ts I am using this component in my Another component say school-home.component.html like this: <app-layout> </app-layout> and it was working fine until I created a Module school-home.module.ts like this: import { NgModule } from '@angular/core'; import { CommonModule } from '@angular/common'; import { SchoolhomeRoutingModule