• iron ion binding • demethylase activity • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen • metal ion binding • caffeine oxidase activity • heme binding • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • enzyme binding • oxidoreductase activity • aromatase activity • electron carrier activity • monooxygenase activity
• response to immobilization stress • 毒素代謝プロセス • steroid metabolic process • response to estradiol • alkaloid metabolic process • response to organic cyclic compound • 肺発生 • 脂質代謝 • exogenous drug catabolic process • epoxygenase P450 pathway • cellular response to cadmium ion • post-embryonic development • monocarboxylic acid metabolic process • response to organic substance • oxidative deethylation • oxidative demethylation • drug catabolic process • response to lipopolysaccharide • メチル化 • steroid catabolic process • omega-hydroxylase P450 pathway • dibenzo-p-dioxin metabolic process • heterocycle metabolic process • 細胞呼吸 • cellular aromatic compound metabolic process • 遺伝子発現調節 • hydrogen peroxide biosynthetic process • monoterpenoid metabolic process • drug metabolic process • xenobiotic metabolic process • oxidation-reduction process • response to drug • porphyrin-containing compound metabolic process • toxin biosynthetic process • cellular response to copper ion • 電子伝達系 • long-chain fatty acid biosynthetic process
^Fontana R, Lown K, Paine M, Fortlage L, Santella R, Felton J, Knize M, Greenberg A, Watkins P (1999). “Effects of a chargrilled meat diet on expression of CYP3A, CYP1A, and P-glycoprotein levels in healthy volunteers”. Gastroenterology117 (1): 89–98. doi:10.1016/S0016-5085(99)70554-8. PMID 10381914.
^ ab Mentioned both in the reference named FASS and were previously mentioned in Wikipedia. Further contributions may follow other systems
^Swedish environmental classification of pharmaceuticals Facts for prescribers (Fakta för förskrivare)
^Edwards DJ, Bernier SM (1996). “Inhibitory effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man”. Life Sciences59 (13): 1025–1030. doi:10.1016/0024-3205(96)00417-1. PMID 8485024.
Meijerman I, Beijnen J, Schellens J (2006). “Herb-drug interactions in oncology: focus on mechanisms of induction”. Oncologist11 (7): 742–52. doi:10.1634/theoncologist.11-7-742. PMID 16880233.
参考文献
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Quattrochi LC, Okino ST, Pendurthi UR, Tukey RH (1986). “Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6.”. DNA4 (5): 395–400. PMID 3000715.
Quattrochi LC, Pendurthi UR, Okino ST, et al. (1986). “Human cytochrome P-450 4 mRNA and gene: part of a multigene family that contains Alu sequences in its mRNA.”. Proc. Natl. Acad. Sci. U.S.A.83 (18): 6731–5. doi:10.1073/pnas.83.18.6731. PMID 3462722.
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Per the Font of Magic feature, sorcerer can use Flexible Casting to create 5th-level spell slots at level 7, even though they are not typically available until level 9. You can transform unexpended sorcery points into one spell slot as a bonus action on your turn. The Creating Spell Slots table shows the cost of creating a spell slot of [5th level is 7] If such a sorcerer levels up while still having this 5th-level spell slot, can they choose a 5th-level spell as the spell they gain upon levelling up? The Spellcasting feature states: Additionally, when you gain a level in this class, you can choose one of the sorcerer spells you know and replace it with another spell from the sorcerer spell list, which also must be of a level for which you have spell slots.
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After the 2018 errata, the disintegrate spell description now reads: A creature targeted by this spell must make a Dexterity saving throw. On a failed save, the target takes 10d6 + 40 force damage. The target is disintegrated if this damage leaves it with 0 hit points. If you were to polymorph an enemy into a rat and then disintegrate it, would the enemy be disintegrated or would it just return to its original form? I know that for Druids, it’s not an instant kill anymore, but is this the case for polymorph as well?
dnd-5e spells polymorph errata
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Recently, I saw a construction of topological invariant for $pi_3(U(n))$ with $ngeq 2$ : $$ N=frac{1}{24pi^2}int_{S^3} d^3x epsilon^{ijk} Tr[(U^{-1}partial_{x_i}U)(U^{-1}partial_{x_j}U)(U^{-1}partial_{x_k}U)] , $$ where $Uin U(n)$ depends on $boldsymbol{x}=(x_1,x_2,x_3)in S^3$ , $epsilon^{ijk}$ is the Levi-Civita symbol, $i,j,k=1,2,3$ , and the duplicated indexes are summed over. It is claimed that $N$ is an integer, but why? Update 02/02/2019 I think I got an argument for $n=2$ . In this case, $U=e^{i varphi} q$ with $qin SU(2)$ . Due to the trace and the Levi-Civita symbol in $N$ , $varphi$ does not contribute to $N$ . As $Tr[q^{dagger}partial_i q]=0$ and $(q^{dagger}partial_i q)^{dagger}=-q^{dagger}partial_i q$ , $q^{dagger}partial_i q$ in geneeral has the form $q^{dagger}partia